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Terre Haute Regional Hospital

Treatments for Peptic Ulcer Disease

The treatment and management of peptic ulcers involves lifestyle changes, medications, alternative and complementary therapies, and surgery. The goals of treatment include:

  • Elimination of Helicobacter pylori infection if present
  • Treating excess bleeding
  • Promoting healing of the ulcer
  • Relieving pain and discomfort
  • Avoiding the development of complications such as perforation, obstruction
  • Preventing ulcer recurrence

Treatment may involve the following:

Lifestyle changesMedicationsAlternative and complementary therapiesSurgery

Revision Information

  • Reviewer: Daus Mahnke, MD
  • Review Date: 06/2016 -
  • Update Date: 05/20/2015 -
  • Meurer LN, Bower DJ. Management of Helicobacter pylori infection. Am Fam Physician. 2002;65(7):1327-36.

  • Peptic ulcer disease. EBSCO DynaMed website. Available at: Updated April 22, 2013. Accessed April 29, 2013.

  • Peptic ulcer disease. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: Updated April 30, 2012. Accessed April 29, 2013.

  • Understanding peptic ulcer disease. American Gastroenterological Association website. Available at: Accessed April 29, 2013.